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Deep Sleep Protocol: DSIP, Orexin B, PE 22-28 and Super Relaxation : A Complete Sleep Stack Guide

August 3, 2026 infa sense

The Foundation: DSIP (The Night Shift Foreman)

At the heart of any advanced sleep stack is Delta Sleep-Inducing Peptide (DSIP). Think of DSIP as the foreman of your night shift. It doesn’t force you to sleep like a sedative; rather, it sets the stage, ensuring that when you do close your eyes, your brain enters the deep, restorative “Delta” wave phase.

DSIP is a naturally occurring neuropeptide that helps regulate the body’s response to stress and manages the sleep-wake cycle. For those dealing with chronic insomnia or fragmented sleep, DSIP acts like a dimmer switch for a bright room. It slowly lowers the metabolic and neurological “lights,” allowing your body to transition into a state of recovery.

Focus on Dosage

We offer DSIP in three tiers to match your specific biological needs:

  • DSIP 5mg: Ideal for maintenance or those new to peptide protocols.
  • DSIP 10mg: The standard dose for addressing persistent sleep disruptions.
  • DSIP 15mg: Advanced support for significant circadian rhythm misalignment.

DSIP 10mg product bottle

The Regulator: Orexin B (The Circuit Breaker)

If DSIP is the foreman, Orexin B is the circuit breaker. In your brain, the sleep-wake cycle is like a “flip-flop” switch. One side is “on” (awake), and the other is “off” (asleep). If this switch is loose, you feel groggy during the day and wired at night: a frustrating state of “tired but wired.”

Orexin B (also known as Hypocretin-B) is vital for stabilizing this switch. While high levels of Orexin keep you alert during the day, having a healthy Orexin system ensures that the transition to sleep is clean and decisive. By supporting the Orexin pathway, you are reinforcing the boundaries of your circadian rhythm, preventing the “daytime” signals from leaking into your “nighttime” recovery.

Focus on the Orexin B 10mg as a tool for Circadian Alignment. It helps ensure that your brain knows exactly when it’s time to be “on” and when it’s time to be “off.”

Orexin B 10mg product bottle